this is a 67 y/o with hx of DM .Accordinig to humself, he had low back pain hx and took Ponstan, Voren and ACT as pain killer usually .3 months ago, his creatinine was still 1.3 and urine protein was negative. howuever , his hba1c was 10 there months ago . he started to have lower leg edema about 1 month after he took extra etodolac. the edematous status was getting progressed . he went to