Author Contributions: Y.-C.Y. and C.-Y.H. conceived and designed the experiments; Y.-C.Y. and C.-Y.H. performedthe experiments; Y.-C.Y. and C.-Y.H. analyzed the data; Y.-C.Y. and C.-Y.H. contributed reagents/materials/analysistools; Y.-C.Y. and C.-Y.H. wrote the paper.Funding: This research received no external funding.Conflicts of Interest: The authors declare no conflict of interest.