In vitro cytotoxicityThe in vitro c

In vitro cytotoxicity
The in vitro cytotoxic potency of thiourea a-aminophosphonate
derivatives 4e5 were evaluated by MTT assay against NCI-H460,
HepG2, A549 and SKOV3 tumor cell lines (with 5-fluorouracil (5-
FU) as the positive control). The values of IC50, the effective concentration
at which 50% of the tumor cells were inhibited, were
calculated to evaluate the antitumor activities. A lower IC50 value
indicated greater antitumor activity. IC50 values of lower than that
of control usually implied effective antitumor activity. The tested
results were shown in Table 1.

結果 (中文) 1:

体外细胞毒性体外细胞毒效价的硫脲一 aminophosphonatemtt 法检测对 nci-h460，评价了衍生品 4e5HepG2、 A549 和 SKOV3 肿瘤细胞系 (与 5-氟尿嘧啶 (5-福) 作为阳性对照)。有效浓度 IC50 值在这 50%的肿瘤细胞有抑制作用，计算评价抗肿瘤活性。较低的 IC50 值表示更大的抗肿瘤活性。IC50 值低于控制通常暗示有效的抗肿瘤活性。测试结果在表 1 所示。

結果 (中文) 3:

体外细胞毒性的体外细胞毒作用
硫脲衍生物α-氨基膦酸酯
4e5分别采用MTT法对NCI-H460、
HepG2、A549和SKOV3肿瘤细胞株（5-氟尿嘧啶（5 -
福）作为阳性对照）。IC50值，其中50%的肿瘤细胞的有效浓度
被抑制，被
计算抗肿瘤活性。一个较低的IC50值
表示更大的抗肿瘤活性。对低于
控制通常隐含的有效的抗肿瘤活性，IC50值。测试结果如表1所示。