The SCL-90-R is divided into nine subscales, and for the present study only the subscales for Depression and Anxiety were used. Further, the SCL-90-R also consists of three indexes – the Global Symptom Index (GSI), the Positive Symptoms Index, and the Positive Symptoms Total Index – all of which were calculated in this study. Depression was assessed using two measures; the Montgomery-Åsberg Depression Rating Scale (MADRS-S) and the Hospital Anxiety and Depression Scale (HADS). The MADRS measures symptoms of depression in terms of specificity, and is developed to measure an individual’s scores at baseline and at follow-up, ie. to follow an individual longitudinally. Scores ≤12 were classified as no depression, scores from 12 to 19 were classified as mild depression, scores from 20 to 34 were classified as moderate depression, and scores ≥35 were classified as severe depression. Depression and anxiety were assessed with the HADS. The HADS measures general distress , i.e. general mental health, such as anxiety/distress as experienced in the individual’s body in general. The HADS consists of an Anxiety subscale (HADS-A) and a Depression subscale (HADS-D). Scores ≤6 indicated no state of anxiety or depression, scores from 7 to 10 indicated possible anxiety or depression, and scores ≥11 indicated probable severe anxiety or depression. The Swedish version of the SCL-90 has found to be reliable and valid. The Swedish version of the MADRS has been validated, and it had adequate internal consistency in this study (Baseline: Cronbach’s α = 0.85; Follow-up: Cronbach’s α = 0.91). The Swedish version of the HADS has been validated, and it had adequate internal consistency in this study (Baseline: Cronbach’s α = 0.87; Follow-up: Cronbach’s α = 0.91), as well the HADS-A (Baseline: Cronbach’s α = 0.80; Follow-up: Cronbach’s α = 0.84) and HADS-D (Baseline: Cronbach’s α = 0.85; Follow-up: Cronbach’s α = 0.90). All instruments, including their psychometric properties, are described in detail in the study protocol.