Cardiovascular disease EditEvidence

Cardiovascular disease Edit
Evidence, in the population generally, does not support a beneficial role for omega-3 fatty acid supplementation in preventing cardiovascular disease (including myocardial infarction and sudden cardiac death) or stroke.[3][19][20] However, omega-3 fatty acid supplementation greater than one gram daily for at least a year may be protective against cardiac death, sudden death, and myocardial infarction in people who have a history of cardiovascular disease.[21] No protective effect against the development of stroke or all-cause mortality was seen in this population.[21] Eating a diet high in fish that contain long chain omega-3 fatty acids does appear to decrease the risk of stroke.[22] Fish oil supplementation has not been shown to benefit revascularization or abnormal heart rhythms and has no effect on heart failure hospital admission rates.[23] Furthermore, fish oil supplement studies have failed to support claims of preventing heart attacks or strokes.[5][6][7]

Evidence suggests that omega-3 fatty acids modestly lower blood pressure (systolic and diastolic) in people with hypertension and in people with normal blood pressure.[24] Some evidence suggests that people with certain circulatory problems, such as varicose veins, may benefit from the consumption of EPA and DHA, which may stimulate blood circulation and increase the breakdown of fibrin, a protein involved in blood clotting and scar formation.[25][26] Omega-3 fatty acids reduce blood triglyceride levels but do not significantly change the level of LDL cholesterol or HDL cholesterol in the blood.[27][28] ALA does not confer the cardiovascular health benefits of EPA and DHAs.[29]

The effect of omega-3 polyunsaturated fatty acids on stroke is unclear, with a possible benefit in women.[30]

結果 (中文) 1:

心血管疾病编辑证据，在人群中一般，并不支持有益作用欧米茄-3 脂肪酸补充在预防心血管疾病 （包括心肌梗死和心脏猝死） 或中风。[] 3[] 19[20] 然而，每日至少一年大于一克的欧米茄-3 脂肪酸补充可能预防心源性死亡、 突然死亡和心肌梗死患有心血管疾病病史的人。[21] 没有起到预防中风或全因死亡率的发展作用见于此人口。[21] 高饮食中含有长链欧米茄-3 脂肪酸的鱼似乎并降低中风的风险。[22] 鱼油补不可以受益血运重建或心律失常，且对心衰住院率没有影响。[23] 此外，鱼油补充剂实验未能支持索赔的预防心脏病发作或中风。[] 5[] 6[] 7有证据表明 ω-3 脂肪酸轻度降低血压 （收缩压和舒张） 在高血压病的人和人与血压正常。[24] 一些证据表明某些循环的问题，如静脉曲张，有的人可能会受益于消费的 EPA 和 DHA，这可以刺激血液循环，增加纤维蛋白，参与血液凝血及瘢痕形成的蛋白质的分解。[] 25[26] 欧米茄-3 脂肪酸降低血甘油三酯水平，但不是显著改变的低密度脂蛋白胆固醇或血液中的高密度脂蛋白胆固醇水平。[] 27[28] ALA 并不赋予 EPA 和 DHAs 心血管健康的好处。[] 29Ω-3 多不饱和脂肪酸对脑卒中的影响是不清楚，可能受益妇女。[] 30

結果 (中文) 3:

心血管疾病编辑证据，在人口一般不支持预防心血管疾病补充ω-3脂肪酸的有益作用（包括心肌梗死和心源性猝死）或中风。[ 3 ] [ 19 ] [ 20 ]然而，补充ω-3脂肪酸大于一克每日至少一年可能对心脏死亡突然死亡，保护，和那些有心血管疾病史的人心肌梗死。[ 21 ]没有保护作用，对脑卒中或死亡率的发展被认为在这一人群。[ 21 ]饮食含有长链ω-3脂肪酸的鱼高会降低卒中风险。[ 22 ]鱼油补充剂并未显示出效益血运重建或异常的心脏节律，并没有对心脏衰竭住院率的影响。[ 23 ]此外，鱼油补充的研究并没有支持预防心脏病发作或中风的索赔。[ 5 ] [ 7 ] [ 6 ]有证据表明，ω-3脂肪酸可轻度降低血压（收缩压和舒张压）在高血压患者和正常血压的人。【24】一些证据表明，某些循环问题的人，如静脉曲张，可能从EPA和DHA的消费利益，这可能会刺激血液循环，增加纤维蛋白故障，一个参与血液凝固和疤痕形成蛋白质。[ 25 ] [ 26 ]ω-3脂肪酸降低血液甘油三酯水平但不显著改变血液中的低密度脂蛋白胆固醇或高密度脂蛋白胆固醇水平。[ 27 ] [ 28 ]阿拉不授予EPA和DHA对心血管健康的好处。[ 29 ]ω-3多不饱和脂肪酸对脑卒中的影响尚不清楚，可能与妇女利益。[ 30 ]