(B) & (C) B16F10 melanoma cells were stimulated with α-MSH (100 nM) for 24 h, and then the melanin
content or intracellular tyrosinase activity were measured after treatment with various concentrations of the flower extract (final concentration 10, 15, 20%; v/v) or arbutin (2.0 mM) for another 24 h.
Results are represented as percentages of control, and data are presented as mean ± S.D. for three separate experiments. Values are significantly different by comparison with control.