Arbutin
Kojic acid
Hydroquinone
L-ascorbic acid
Inhibitory effects of arbutin (.) on tyrosinase activity in human melanocytes. Cultures of 10 000 cells cm2 were incubated with these agents for 3 days. Tyrosinase activity was measured using L-DOPA (1103 mol l1) as the substrate.
The results are expressed as percentage of inhibition with respect to the untreated control