It is known that amino acids and peptides are being taxonomically natural, physiologically nontoxic and chemically multifunctional, their rationalized conjugates with biologically active synthetic organic agents, are hypothesized to be more potent, particularly less toxic than their parent biologicals [8]. Further, thiophene de-rivatives have received interest because of their potential pharmacological utility and their incorporation in syn-thetic peptides [9-11]. Several thiophene derivatives are
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known and have been used as antibiotic, anti-allergic, anti-migraine, antioxidant agents [12-14].