Reviews of available safety data report inconsistent findings. In a systematic review of randomized-controlled trials (RCTs) of YBIs, the overall frequency of AEs was relatively low (2.2%), and yoga practice was not associated with more AEs compared to other exercise-basedinterventions.32 However, a review of epidemiological observational studies reported high rates of yoga-related AEs, with a lifetime prevalence of yoga-related injuries ranging from 21.3% to 61.8%.31 The large range may be due to the different time periods assessed: some studies assess for lifetime prevalence of AEs and others asses for AEs overthecourseofastudy period.Regardless ofthetimeframeassessed, yoga-related AEs tended to be mild, transient, and musculoskeletal in nature.31 Of note, the predominance of posture-related AEs reported in the YBI literature is likely a reflection of the emphasis that modern hatha yoga practices place on physical postures. Younger populations reported more frequent AEs (likely due to more intense practice), while elderly populations experienced more SAEs, which the authors explain is likely due to a decreased ability to handle physical strain and longer recovery times following AEs.31,34 These findings speak to the need to evaluate the safety of yoga practice across diverse populations, with a focus on age, mobility, overall physical health, and mental health. The majority of reviews that examine the safety of YBIs do not do so explicitly among depressed populations and do not examine AEs that might be specific to individuals with depressive disorders, such as worsening symptoms of depression or suicidality.