Serum and plasma chemistry profiles are shown in Table 5. Cows in CON had greater concentrations of serum cholesterol (P < 0.001) and plasma SOD (P = 0.04) and tended to have increased whole-blood BHB concentrations (P = 0.06) compared with cows in POS (POS vs. CON). Cows in POS tended to have increased plasma albumin concentrations (P = 0.09) compared with cows in CON (POS vs. CON). There was a positive linear treatment effect for plasma glutamate dehydrogenase (P = 0.05) as concentration of adsorbent in the diet increased. A positive linear trend was present for plasma alanine aminotransferase (P = 0.06) as concentration of adsorbent in the diet increased. No treatment × day interactions were observed for any blood variables (P > 0.11).