The onset of peptic ulcer (PU) is characterized by seasons, with a high incidence in winter and spring and a low incidence in summer[1-8]. We made a correlated analysis of the relationship between detectable rate of PU (DRPU) from 1992 to 1997 in Nanning and a regressive analysis of the meteorological factors (MFs) in the same period. We found that DRPU was closely related to the seasons and MFs.