In this study, Pluronic F-127 has provided a suitable 3-D
environment for BM-MSC to differentiate into adipocytes
in the presence of adipogenic media and even in the
absence of differentiation media. It has also been reported
that Pluronic F-127 can interact with heparin [38].
Considering the significant importance of heparin in
controlled release applications, it might be beneficial to
load different angiogenic and adipogenic growth factors in pluronic F-127 for adipose tissue engineering