Chronic inflammation of the lung(mouse)(Reference)According to the long-term carcinogenicity test results of the Japan Bioassay Research Center, exposure of ITO grinding powder to male and female rats at 0.01, 0.03, 0.1 mg / m 3 concentration for 104 weeks resulted in the lowest concentration of 0.01 mg / m 3 Alveolar proteinosis in the rat, hyperplasia of the alveolar epithelium, fibrosis of the alveolar wall, and increased incidence of alveolar proteinosis in mice were observed. 3.0×10-4mg/m3Calculation formula :0.01mg/m3(LOAEL)×1/25(UF)× 6/8(Work revision)=3.0×10-4mg/m3LOAEL:Prolonged long-term carcinogenicity test by inhalation of rats by Japan Bioassay Research CenterUF:LOAELConversion of NOAEL(10)、Specific difference(2.5)