EvidEncE-basEd answEr A Can yoga reduce symptoms of anxiety and depression? Yes, yoga can reduce symptoms of anxiety and depression (strength of recommendation [SOR]: B, systematic reviews of randomized controlled trials [RCTs] with significant heterogeneity). Across multiple RCTs using varied yoga interventions and diverse study populations, yoga typically improves overall symptom scores for anxiety and depression by about 40%, both by itself and as an adjunctive treatment. It produces no reported harmful side effects.