The swelling percentage of the SCN nanoparticle formulation was also monitored at different time intervals (Figure 3). It was observed that all nanoparticles rapidly swelled within 7.2 minutes in saline at a pH level of 1.2. The mucoadhesiveness of the nanoparticles was reported earlier, and the cohesiveness of the polymers was represented by the swelling index [25]. Overall, it was found that liquid in the stomach was absorbed by the nanoparticles. The capillary action of the mucosa contributes to stronger adhesion. SCN formulation swelling was around 168% ± 15%.