activator proteins bind to distal control elements grouped as an enhancer in the DNA. this enhancer has three binding sites, each called a distal control elements.a DNA-bending protein brings the bound activators closer to the promoter.general transcription factors, mediator factor protein, and RNA polymerase two are nearby.the activators bind to certain mediator proteins and general transcription fractors, helping them form an active transcription initiation complex on the promoter.