The ingredients in Passion D’tox is absorbed and released slowly by the body over a period of 6-8 hours. And because your body will be “detoxifying” itself and will be cleaning out the system at this time period, it is best to take it before bedtime so you could wake up in the morning and flush the wastes in the bathroom. You might want to avoid taking it in the morning though so to avoid “bathroom-trips” trouble.