The chronic treatment with argan oil reduced the increase in glucose levels in glucose fed rats so that the blood glucose in argan oil glucose-treated rats was significantly decreased compared glucose-fed rats (P < 0.05) or with rats treated with glucose combined with corn oil (P < 0.01). As shown in Figure 3, plasma insulin levels were increased by 108% (P < 0.01) in glucose-fed rats. Simultaneous oral feeding with argan oil decreased by 52% the rise in plasma insulin; however, this decrease was not significant. It is noteworthy that the value of argan glucose–fed rats did not statistically differ from that in control rats. The oral feeding with corn oil normalized (P < 0.05) plasma insulin levels in 5-wk glucose-treated rats.