I checked my old e-mail corresponde

I checked my old e-mail correspondences. Aquair Evolution was started with the 1,000ppm formula but it was reduced to 600ppm thereafter. But it is NOT as the result of the evaluation that the lower concentration is as good as the original one in terms of efficacy. It was solely for the purpose of cost reduction.

That means the product approval should include 1,000ppm. The Dr. Salmon study which I sent to you in the previous e-mail as File #2 was based on the 1,000ppm concentration. If I remember correctly, NOF told me even higher level of concentration as having better efficacy. But I am not 100% sure whether it is also true for the application like ours. And I also could not find a proof that CooperVision’s product approval includes the concentration level higher than 1,000ppm.

So, I am interested in the result of the test by your R&D team. But evaluating the property like the contact angle only at the static stage may not result in the difference by the different level of concentration. It is because higher concentration level may, or may not, mean that MPC can be captured in the sponge-like structure of the hydrogel lens longer than the lower concentration. So we may need to evaluate the performance of the lens using a method like this in the more dynamic and simulating the condition of the lens in the eye. (http://susos.com/uploads/companydirectory/id19/Friction_Measurements_on_Contact_Lenses.pdf)

結果 (繁體中文) 2:

我檢查了我的舊電子郵件書信來往。Aquair演進開始與1,000ppm式，但它減少了到600ppm的其後。但它是不作為評價的結果，該低濃度一樣好原來在功效方面。這是專為降低成本的目的。這意味著該產品的批准應包括1,000ppm。我在以前的電子郵件作為文件＃2發送到你的醫生鮭魚研究是基於1,000ppm的濃度。如果我沒有記錯，NOF告訴我，濃度更高的水平具有較好的療效。但我不是100％肯定它是否也適用於像我們這樣的應用程序。而且我也找不到一個證明，酷柏光學的產品審批包括超過1,000ppm濃度較高的水平。所以，我在你的研發團隊有興趣測試的結果。但僅在靜態階段評價像的接觸角的特性可能不會導致由不同級別的濃度的差。這是因為較高的濃度水平可以，或可以不意味著MPC所用的水凝膠鏡片的海綿狀結構被捕獲長於濃度較低。所以，我們可能需要使用這樣的方法，在更動態的和模擬的眼睛晶狀體的條件來評價透鏡的性能。（http://susos.com/uploads/companydirectory/id19/Friction_Measurements_on_Contact_Lenses.pdf）

結果 (繁體中文) 3:

我翻查我的老E-mail書信來往。 aquair演變,開始與1,000ppm公式,但它是減至600ppm之後。 但這並不是由於較低的評價,這是一個良好的集中在一個原條款的效力。 這純粹是為了降低成本。

這意味著批准應包括1,000ppm的產品。 《Dr.鲑魚研究,我給你的E-mail,以前的文件是根據#2 1,000ppm濃度。 如果我沒有記錯的話,北歐牙科學協會告訴我甚至更高水平的濃度,有更好的療效。 但我不肯定是否100%,也是真正的應用,例如我們。,我也不可能找到一個証明coopervision的產品包括批准的濃度水平高於1,000ppm。

,所以,我很有興趣的測試結果r&d隊由你。 但評價的物業的聯系等角度來看,隻有在靜態階段的差異可能不會導致在不同的濃度。 這是因為高濃度可能,或可能不可以,意味著壟斷和價格在捕獲的海綿式的結構hydrogel鏡頭再於較低的濃度。 因此,我們可能需要評估的鏡頭的業績,使用一個方法,更有活力和模擬的鏡頭的條件,在眼睛的。 (http://susos.com/uploads/companydirectory/id19/friction_measurements_on_contact_lenses.pdf)