10. ConclusionIncomplete involution

10. ConclusionIncomplete involution of the embryonic tubular structure known as the urachus allows for persistence of UA in both the pediatric and adult population. Patients may present with congenital UA or acquired urachal remnant diseases. Congenital UA can be divided into five groups: patent urachus, umbilical-urachal sinus, vesicourachal diverticulum, urachal cyst, and alternating sinus. A patent urachus is usually detected at birth. However, the remaining four UA can persist and have the potential to become infected or undergo malignant transformation, causing neoplasm development. Infections and neoplasm cause quiescent UA to become symptomatic, occurring at any time in an individual's life, and are referred to as acquired urachal remnant diseases. The current literature does not provide conclusive data or uniform protocols regarding diagnostic evaluation and treatment options. This may be a result of the rarity of UA and that the majority of data is obtained from case studies. These cases studies provide valuable information, however, they are perpetuating discrepancies in diagnosis and management seen in the current literature. Therefore, future studies should be interested in longitudinal large-scale cohort studies in an attempt to establish optimal protocols.Conflict of interestThe authors have no conflicts of interest to declare.Ethical statementNo humans or animals were part of this study. All authors contributed to and approved this manuscript.Financial disclosureWe have received no funding for this manuscript. None of the authors have conflicts of financial interest.References

結果 (繁體中文) 1:

10. Conclusion
Incomplete involution of the embryonic tubular structure known as the urachus allows for persistence of UA in both the pediatric and adult population. Patients may present with congenital UA or acquired urachal remnant diseases. Congenital UA can be divided into five groups: patent urachus, umbilical-urachal sinus, vesicourachal diverticulum, urachal cyst, and alternating sinus. A patent urachus is usually detected at birth. However, the remaining four UA can persist and have the potential to become infected or undergo malignant transformation, causing neoplasm development. Infections and neoplasm cause quiescent UA to become symptomatic, occurring at any time in an individual's life, and are referred to as acquired urachal remnant diseases. The current literature does not provide conclusive data or uniform protocols regarding diagnostic evaluation and treatment options. This may be a result of the rarity of UA and that the majority of data is obtained from case studies. These cases studies provide valuable information, however, they are perpetuating discrepancies in diagnosis and management seen in the current literature. Therefore, future studies should be interested in longitudinal large-scale cohort studies in an attempt to establish optimal protocols.

利益衝突
的作者有沒有利益申報衝突。

倫理聲明
沒有人類或動物研究的一部分。所有作者貢獻和批准了這一手稿。

財務披露
，我們已經收到了這份手稿沒有資金。作者都沒有經濟利益的衝突。

參考

結果 (繁體中文) 2:

10. 結論
胚胎管狀結構（稱為urachus）的不完全卷積允許UA在兒科和成人群體中持續存在。患者可能患有先天性 UA 或後天性烏拉爾殘餘疾病。先天性UA可分為五組：專利尿道、臍帶-烏拉爾鼻利、囊腫、尿囊囊腫和交替鼻利。專利烏拉丘通常在出生時被檢測到。然而，其餘四個UA可以持續，並有可能被感染或惡性轉化，導致腫瘤發展。感染和腫瘤導致靜止的UA成為症狀，發生在個人生活中的任何時間，並被稱為獲得性烏拉查爾殘餘性疾病。目前的文獻沒有提供有關診斷評估和治療方案的決定性資料或統一協定。這可能是由於UA的罕見，而且大部分資料來自案例研究。這些病例研究提供了寶貴的資訊，然而，它們使當前文獻中的診斷和管理差異長期存在。因此，未來的研究應該對縱向大規模佇列研究感興趣，以試圖建立最佳的規程。

利益衝突
提交人沒有利益衝突可申報。

道德聲明
沒有人類或動物參與這項研究。所有作者都為這份手稿做出了貢獻並獲得批准。

財務披露
我們沒有收到這份手稿的資金。提交人中沒有一個有財務利益衝突。

引用

結果 (繁體中文) 3:

10個。結論
不完全複卷的胚胎小管結構稱為臍尿管允許在兒童和成人群體中的尿酸持續存在。患者可能會出現先天性尿囊炎或後天性臍尿管殘餘疾病。先天性UA可分為五組：臍尿管未閉組、臍尿管竇組、膀胱尿道憩室組、臍尿管囊腫組和交替竇組。臍尿管未閉通常在出生時被發現。然而，剩下的四種UA可以持續存在，並有可能被感染或發生惡性轉化，導致腫瘤發展。感染和腫瘤導致靜止性尿毒癥成為症狀，發生在個人生活的任何時候，並被稱為獲得性臍尿管殘餘疾病。現時的文獻沒有提供關於診斷評估和治療選擇的結論性數據或統一的方案。這可能是由於UA的罕見性以及大多數數據是從案例研究中獲得的。這些案例研究提供了有價值的資訊，然而，它們在診斷和管理方面的差异一直存在於現有文獻中。囙此，未來的研究應關注縱向大規模隊列研究，試圖建立最佳方案。
利益衝突
作者沒有利益衝突要聲明。
道德聲明
沒有人或動物是這項研究的一部分。所有的作者都參與並準予了這篇手稿。
財務披露
我們沒有收到這份手稿的資金。所有作者都沒有經濟利益衝突。
工具書類