Process for low migration qualification in the food, pharma and medicalindustryDefinition of migration, set-off, low migration inks and the printing processMigration substances can modify products, its odor, active substance intensity of a pharmaproduct, and taste. They can be unhealthy. To understand migration, let us begin by differentiatingbetween migration and set-off, and then define low-migration.MigrationMigration is the diffusion of the remaining ingredients of the cured ink film through thepackaging material into the filling product.Set-offSet-off, is the transfer of remaining ink substances from the printed surface of a packagingsubstrate to its unprinted, product-contact surface. Set-off occurs when the two surfaces comeinto contact, i.e. when the substrate material has been stacked or wound onto rolls. In general,set-off is not visible, as only molecules of the ink substances are transferred.