So, Puerto Rico is considering two different options:
1) Introducing only mW’s with the goal of (temporarily) reducing the overall mosquito
population.
2) Introducing both mW’s and fW’s, with the goal of eventually replacing most
“regular” mosquitoes by Wolbachia-carrying mosquitoes that are incapable of
transmitting Zika.
Of course, you can also recommend a time-dependent strategy, switching between the
above options. Your plan should cover 5 years and guarantee that
A. The total number of Zika-infected pregnant women in Puerto Rico over these 5
years should not exceed 10000. (Note: based on CDC statistics, as of right now,
about 22 pregnant women get newly Zika-infected in Puerto Rico every day.)
B. After the first year, the number of newly infected people per day should not
exceed 300. (Note: as of right now, the number of newly infected Puerto Ricans
is estimated to be 600 per day, including the 80% of infections that are
asymptomatic and usually go unreported.)