Dose effect curves for 552 temporal lobes in patients with NPC.Dashed lines indicate the 95% CI of the tolerance dose at a given effect probability level. To visualize the underlying data, incidence rates were calculated forintervals of 10-Gy equivalents (GyE) and were displayed numerically (presented along the curves as number of temporal lobes that responded/number of irradiated temporal lobes), as well as graphically (circles). Data points were assigned to the mean dose of each 10-Gy equivalent interval.